phenethylamine25E-NBOH 1.2mg Blotters
Arylcyclohexylamines, which are also known as arylcyclohexamines or arylcyclohexanamines, possess properties that vary in terms of their ability to inhibit dopamine reuptake, act as NMDA receptor antagonists, and act as agonists for -opioid receptors. In addition, it has been reported that certain of these agents exhibit actions that are agonistic for receptors, antagonistic for nACh receptors, and agonistic for D2 receptor. Blockade of the dopamine transporter mediates stimulant and euphoriant effects as well as psychosis in high amounts; and activation of the -opioid receptor causes analgesic and euphoric effects. Antagonization of the NMDA receptor confers anesthetic, anticonvulsant, neuroprotective, and dissociative effects. It's possible that stimulating the alpha and dopamine D2 receptors is also responsible for the hallucinogenic and psychotomimetic effects. ...
History and possible effects of Arylcyclohexylamines
It is believed that phencyclidine (PCP) was the first arylcyclohexylamine with recognized anesthetic properties. However, several arylcyclohexylamines were described before PCP in the scientific literature, beginning with PCA (1-phenylcyclohexan-1-amine), the synthesis of which was first published in 1907. PCE was discovered in 1953, and PCMo (4-(1-phenyl-cyclohexyl)-morpholine) was discovered in 1954. PCMo was referred to as a powerful sedative at the time of its discovery. At Parke-Davis, arylcyclohexylamine anesthetics were the subject of extensive research beginning in 1956 with the synthesis of phencyclidine and continuing with the discovery of the related compound ketamine in later years. The decade of the 1970s saw the introduction of these compounds, particularly PCP and its analogues, as illegally used recreational drugs due to the dissociative hallucinogenic and euphoriant effects that they have. Since then, the category has grown thanks to both legitimate scientific research into stimulant, analgesic, and neuroprotective agents, as well as the efforts of underground chemists looking to develop new recreational drugs.
Structure of Arylcyclohexylamines
A cyclohexylamine unit that has an aryl moiety attached to it is the component that makes up an arylcyclohexylamine. The aryl group is situated in the terminal position relative to the amine. The aryl moiety is typically represented by a phenyl ring, albeit one that may contain additional substitution depending on the circumstances. Secondary amines, such as methylamino or ethylamino, or tertiary cycloalkylamines, such as piperidino and pyrrolidino, are the most commonly encountered N-substituents. The amine is typically not primary.
Arylcyclohexilamines are available for purchase in powder, blotter, or pellet form through our online store, FreshChems. These can be used for research purposes, such as studying neuro-dissociative disorders or situations in which the subject's perception of reality could be altered. In addition, the treatment of inflammatory diseases, particularly those that are chronic, and those that can affect the central nervous system and cause discomfort or even pain could be another area of investigation that could be pursued.
On the other hand, arylcyclohexylamines can be utilized in the investigation of identity disorders as well as neurodegenerative diseases because they are substances that interact with the NMDA receptors and dopamine. However, despite the fact that these properties are described in general terms, we recommend conducting studies on individual chemicals because the way in which they interact with receptors and other neurotransmitters can vary depending on which chemical is being considered.
Special terms and conditions to buy Arylcyclohexylamines
Every one of our research chemicals, including arylcyclohexylamines, is only offered for sale for use in the context of analytical and laboratory settings. Please check the legal status of our products in your country before placing an order if you plan to purchase them from a location other than the Netherlands. You are solely responsible for ensuring that your purchases are in accordance with the laws of the jurisdiction in which you are located.
Please make sure to read the product description before placing an order for a research chemical belonging to the Arylcyclohexilamine family. This will allow you to determine whether or not the chemical is available for purchase in your country. Another option would be to sign up for an account with us and then update your profile with the shipping address you prefer to use. Because of this, the system won't let you add the product to your shopping cart if it has been restricted from sale in your country.
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Your order with Arylcyclohexylamines will be considered accepted as soon as we have received the payment, and a new email notification will be sent to you at that time. Your order will be shipped the following business day if payment is received before 16 hours Central European Time (CET).
You can find more info in the wikipedia page.
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